I’m sorry, I don’t understand the above responses. Any idea what we should do/whats wrong?
Yes. I have an idea of what could be wrong but we need more info. Do this.
Make sure the fuse that is blowing is good.
Connect your power at a campground or if you have a 50A outlet at home.
Check the fuse.
If the fuse has not blown, at the pedestal where your 50A male plug is at, leave it plugged in, turn off the breakers there, at the pedestal.
Check the fuse.
If the fuse is still good, not blown, turn the breakers back on.
Check the fuse.
Without turning off the breakers at the pedestal where your 50A cable is plugged in, just unplug it with the breaker on.
Check the fuse. If it is blown we can move on to the next steps.
If it is not blown, meaning it happens after you disconnect and while you are towing, and only while you are on 12V power, the answer is easier.
The fuse that is blowing, the one you replaced 6 times, what circuit/device does it protect? Lights? 12V fridge? Something else? That can tell us a lot. What doesn't work?